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Rakam: Distributed Analytics API
Today, most of the “big data” applications needs to compute data in real-time since the Internet develops quite fast and the users expect the get reactions from the applications simultaneously. This rule is valid for almost all types of applications. When a user interacts with a commercial website by looking a product, the website should be able to show her related products for increasing its conversion rates. For a CRM application, the users should be able to solve their problem using that application. And most the time, these actions need aggregation computations. The aim of our project is to provide a high-performance scalable computational engine that is flexible and can be adapted to any type of applications. The system collects the events with collection API and continuously processes them on the fly with using pre-aggregation rules submitted by Analysis API.
Burak Emre Kabakcı
Engineering Fasciculin-II to treat Alzheimer's Disease Related Symptoms
Alzheimer’s disease is characterized by death of cholinergic neurons, which secrete the neurotransmitter acetylcholine. This results in a loss of the total amount of acetylcholine circulating in neural networks. Modern drugs target acetylcholinesterase so as to inhibit its function, allowing for increased transmission of acetylcholine in cholinergic synapses. The aim is that an increase in cholinergic activity leads to an increase in cognition. However, these drugs only bind temporarily and have consequential problems that make modern AChE inhibitors of little effect. The main goal of our project is to engineer a snake toxin, fasciculin-II, capable of crossing the blood brain barrier and inhibiting acetylcholinesterase with enough affinity that it increases cholinergic transmission without yielding toxic outcomes. This fasciculin binds to the peripheral acetylcholinesterase found in neuromuscular junctions and causes rapid twitching. Fasciculin-II binds to acetylcholinesterase very tightly with the use of many charged residues and hydrophobic residues and we would like to optimize this interaction so that it may serve a therapeutic purpose in patients of AD.
Second Project: <Name>.
This project will discuss the usage of the logical programming language called Prolog to solve a diabolic magic squares made with 4 by 4 squares and Python as a front-end. A diabolic magic squares are matrix of 4 rows and 4 columns which have unique numbers on each cell from 1 to 16. This project will implement the solution of this problem using logical deduction.
Analyzing elliptically polarized light using Fresnel Rhomb
The aim of the experiment is to study elliptically polarized light using a Fresnel rhomb and to determine the ratio of semi major axis to the semi minor axis of the various elliptically polarised light forms for different angles of plane polarised incidence at the rhomb
Alan Raj Jeffrey